Mechanistic modelling for ecotoxicology and ecology

DEBtox Researc

Type of activities offered by DEBtox Research

DEBtox Research specialises in the development and application of mechanistic models in eco(toxico)logy. My focus is on working with models based on Dynamic Energy Budget (DEB) theory (at the moment especially DEBkiss) and the General Unified Threshold model for Survival (GUTS), but I am also experienced in toxicokinetic modelling. My modelling expertise comes with an extensive knowledge of the statistics associated with fitting models to data and the calculation of confidence intervals (incl. intervals on model predictions). And, last but not least, I love to write, as you can see from my publication record.

These models can be applied to a wide range of species (basically: all), and an enormous range of fundamental and applied research questions. You can think of studies aimed at understanding stressor effects of toxicants and environmental factors (e.g., ocean acidification, starvation), but also more fundamental topics (e.g., biology of ageing, linking the molecular level to life-history traits, inter- and intra-species differences in life history). I am happy to discuss the possibilities of these models to address your research question, so please contact me if you are interested.
I prefer to work on multi-year research projects with a scientific (or applied-scientific) character, that include the possibilities for dedicated experimental work to be performed (I do not have access to laboratory facilities myself). I can also be hired for a single data analyses (or scientific consult) with full confidentiality, albeit at a higher hourly rate. My current range activities include:
  • Data analysis and predictions using models, specifically DEBkiss-based or GUTS models, but also TK models.
  • Model and code development for specific TK and TKTD problems (in Matlab-BYOM).
  • Scientific advice on the subject of modelling and model applications. This includes advise on the most appropriate design of experimental tests for parameterising models.
  • Publication in scientific peer-reviewed journals.


Even when I have insufficient time available to work on your project within a given time frame, it is useful to contact me. I regularly collaborate with various contract labs as well as various university groups and research organisations.

Courses offered and teaching

In 2023, I decided to severely limit my teaching activities. However, feel free to contact me if you have specific training needs. If I cannot help you, I may know other scientists that can.

On the web site, there is a section on courses related to TKTD modelling that I will try to keep up to date. Specifically, I would like to draw your attention to the summer/autumn course on TKTD modelling (with some TK and GUTS, but specific focus on the DEBkiss model). If you want to learn about the basics of TKTD modelling, DEB theory, coding and fitting, in a friendly way: this is the course for you. More information.

There are often some course opportunities for GUTS and openGUTS as well. Look at the openGUTS website for more details. We also offer a DIY, on-demand, on-line short course on the openGUTS software.

DEBtox Research,, Chamber of Commerce Utrecht 62405055, email: tjalling (at)