Mechanistic modelling for ecotoxicology and ecology

DEBtox Researc

Welcome to DEBtox Research

DEBtox Research is the private company that I (Tjalling Jager) operate since January 2015 to offer my knowledge and expertise on mechanistic modelling to customers. My mission is to increase the scientific foundation of ecotoxicology, environmental risk assessment, and life-history ecology, by the application of mechanistic models. Mechanistic modelling attempts to provide a (simplistic) explanation for the observed behaviour of the organism, rather than just describing it. Thereby, we gain a deeper understanding of the organism and the stressors affecting it. In turn, this understanding can help us to make educated extrapolations to untested situations. This is where fundamental research meets application!

My specialty is in the development and application of toxicokinetic and toxicodynamic models (at the level of the individual), in particular models based on Dynamic Energy Budget (DEB) theory and the General Unified Threshold model for Survival (GUTS). These models can be applied to a wide range of species (basically: all), and an enormous range of fundamental and applied research questions. More information on the type of activities that I have to offer can be found on the activities page.

I also maintain the site, which contains much more detailed information about these models, as well as links to free e-books, software, and lists of relevant publications. This website is dedicated to my project activities.


  • The 5th international DEB symposium will be 31 May-2 June in Tromsø, Norway. More information.
  • Roman Ashauer and myself will be collaborating in a CEFIC-LRI funded project centered on GUTS. More information over here.
  • The summer course on dynamic modelling of toxic effects was held 9-16 August 2016 in Denmark. We plan to give the course again 2018. More information.

DEBtox Research,, Chamber of Commerce Utrecht 62405055, email: tjalling (at)