The increasing use of chemicals to treat farmed salmon
against the crustacean ectoparasitic salmon louse (Lepeophtheirus
salmonis) in Norwegian salmon farms is a concern for
the authorities, the industry (aquaculture and coastal
fisheries) and the public. The proposed project will provide
valuable new information about how a keystone species in the
marine ecosystem, the commercially and culinary important
northern shrimp (Pandalus borealis) responds to
repeated pulse exposures to combinations of pesticides used
for delousing salmon. Marine organisms living in areas with
salmon farms could be exposed repeatedly to mixtures of
pesticides. Since data on repeated pulse or fluctuating
exposures are very rare in the literature, we will
investigate the effects of two combination treatments
recommended for efficient delousing in Norwegian salmon
farms. In parallel to the shrimp experiments, we will
evaluate if blue mussels (Mytilus edulis) are
sensitive enough to be used for monitoring discharges of the
tested chemicals by using valve gape behaviour and
accumulation of pesticides.
The toxicokinetic-toxicodynamic model (TKTD) GUTS
represents the state-of-the art in dynamic modelling for the
endpoint survival. The GUTS model will be used to explain
the dynamic mortality pattern in Northern shrimp exposed to
the chemical mixtures. The resulting model will then be used
to extrapolate to mortality patterns in scenarios not tested
in the laboratory. Data and results from previous projects
will be used as an input in the model development and
parametrization. The GUTS model will be calibrated based on
the available toxicity data for the single chemicals, and
used to predict the behavior of the mixture. The deviations
from the predictions will provide information on the
existence and importance of interactions of the mixture
components. As the animals are growing in the toxicity
tests, special care will be taken to include the effects on
growth on toxicokinetics in the GUTS model.
The northern shrimp, Pandalus borealis.
Output: Publications (as first or co-author)
- Bechmann RK, M Arnberg, A Gomiero, S Westerlund, E
Lyng, M Berry, T Agustsson, T Jager, L Burridge (2019).
Gill damage and delayed mortality of Northern shrimp (Pandalus
borealis) after short time exposure to
anti-parasitic veterinary medicine containing hydrogen
peroxide. Ecotox Environ Saf 180:473-482. https://doi.org/10.1016/j.ecoenv.2019.05.045
Output: Presentations (as presenter and as contributor)
- Assessing effects of salmon lice treatment (H2O2) on
shrimp populations in a multi-stressor environment. Moe
J, T Jager, D Hjermann, E Ravagnan, R Bechmann.
Platform presentation at SETAC Toronto 2019.
- Hydrogen peroxide effects on Northern shrimp: dynamic
modelling of mortality. Jager T, J Moe, DØ Hjermann, E
Ravagnan, RK Bechmann. Planned poster presentation at
the 30th SETAC
Europe conference in Dublin, Ireland, 3-7 May
- Presentation by Jannicke Moe at the 30th SETAC Europe
conference in Dublin, Ireland, 3-7 May 2020.
Details will follow.